Inheritance of One Gene 🧬
1. Mendel’s Classic Monohybrid Cross 🌿
Mendel crossed tall pea plants (TT
) with dwarf plants (tt
). Every F1 seedling grew tall, showing that the tall trait (T
) dominates the dwarf trait (t
). :contentReference[oaicite:0]{index=0}
- F1 genotype:
Tt
(all tall) - F2 phenotypes after self-pollinating
Tt × Tt
: 3 tall : 1 dwarf - F2 genotypes:
TT : Tt : tt = 1 : 2 : 1
The same 3 : 1 phenotypic pattern appeared for every contrasting pair of traits Mendel studied. :contentReference[oaicite:1]{index=1}
2. Genes, Alleles & Helpful Terms 📖
- Gene
- A heritable unit that carries information for a trait.
- Alleles
- Different forms of the same gene (e.g.,
T
andt
). - Genotype
- The allele pair an organism has (
TT
,Tt
ortt
). - Phenotype
- The visible trait (tall or dwarf).
- Homozygous
- Both alleles identical (
TT
ortt
). - Heterozygous
- Alleles different (
Tt
).
3. Punnett Square Magic 📊
T | t | |
---|---|---|
T | TT | Tt |
t | Tt | tt |
Probability view: \( \Bigl(\tfrac{1}{2}T + \tfrac{1}{2}t\Bigr)^{2} = \tfrac{1}{4}TT + \tfrac{1}{2}Tt + \tfrac{1}{4}tt \) 🍀
4. Mendel’s Two Big Rules ⚖️
- Law of Dominance – In a heterozygote, one allele (dominant) masks the other (recessive). :contentReference[oaicite:2]{index=2}
- Law of Segregation – Allele pairs separate during gamete formation, so each gamete carries only one allele. :contentReference[oaicite:3]{index=3}
5. Test Cross 🔍
To uncover whether a tall plant is TT
or Tt
, cross it with a recessive (tt
) plant:
- If all offspring are tall → parent was
TT
. - If offspring split 1 tall : 1 dwarf → parent was
Tt
.
Quick, definitive, and NEET-friendly! :contentReference[oaicite:4]{index=4}
6. Beyond Simple Dominance 🌈
6.1 Incomplete Dominance 🌸
Snapdragon cross: red (RR
) × white (rr
) → F1 pink (Rr
). Self-pollination gives 1 red : 2 pink : 1 white. The heterozygote shows an intermediate color. :contentReference[oaicite:5]{index=5}
6.2 Co-dominance 🩸
Human ABO blood group gene I
has three alleles: IA
, IB
, i
.
Genotype | Blood Type |
---|---|
IAIA, IAi | A |
IBIB, IBi | B |
IAIB | AB (both sugars expressed) |
ii | O (no sugar) |
With IAIB
, both A and B sugars appear together—no blending, true co-dominance. :contentReference[oaicite:6]{index=6}
6.3 Multiple Alleles & Pleiotropy 🌀
- ABO system shows multiple alleles—three versions of one gene exist in the population.
- One gene can affect more than one trait. Example: pea seed gene
B/b
controls both starch-grain size and seed shape. :contentReference[oaicite:7]{index=7}
Important Concepts for NEET 🚀
- The monohybrid 3 : 1 phenotype and 1 : 2 : 1 genotype ratios.
- Law of Segregation explains why recessive traits re-appear in F2.
- A test cross (dominant × recessive) instantly reveals unknown genotypes.
- Recognize complete dominance vs. incomplete dominance vs. co-dominance.
- Multiple alleles (ABO) and pleiotropy (starch gene) widen inheritance patterns.
Happy studying and keep exploring genetics 😊!