Inheritance of One Gene 🧬

1. Mendel’s Classic Monohybrid Cross 🌿

Mendel crossed tall pea plants (TT) with dwarf plants (tt). Every F1 seedling grew tall, showing that the tall trait (T) dominates the dwarf trait (t). :contentReference[oaicite:0]{index=0}

  • F1 genotype: Tt (all tall)
  • F2 phenotypes after self-pollinating Tt × Tt: 3 tall : 1 dwarf
  • F2 genotypes: TT : Tt : tt = 1 : 2 : 1

The same 3 : 1 phenotypic pattern appeared for every contrasting pair of traits Mendel studied. :contentReference[oaicite:1]{index=1}

2. Genes, Alleles & Helpful Terms 📖

Gene
A heritable unit that carries information for a trait.
Alleles
Different forms of the same gene (e.g., T and t).
Genotype
The allele pair an organism has (TT, Tt or tt).
Phenotype
The visible trait (tall or dwarf).
Homozygous
Both alleles identical (TT or tt).
Heterozygous
Alleles different (Tt).

3. Punnett Square Magic 📊

Tt
TTTTt
tTttt

Probability view: \( \Bigl(\tfrac{1}{2}T + \tfrac{1}{2}t\Bigr)^{2} = \tfrac{1}{4}TT + \tfrac{1}{2}Tt + \tfrac{1}{4}tt \) 🍀

4. Mendel’s Two Big Rules ⚖️

  1. Law of Dominance – In a heterozygote, one allele (dominant) masks the other (recessive). :contentReference[oaicite:2]{index=2}
  2. Law of Segregation – Allele pairs separate during gamete formation, so each gamete carries only one allele. :contentReference[oaicite:3]{index=3}

5. Test Cross 🔍

To uncover whether a tall plant is TT or Tt, cross it with a recessive (tt) plant:

  • If all offspring are tall → parent was TT.
  • If offspring split 1 tall : 1 dwarf → parent was Tt.

Quick, definitive, and NEET-friendly! :contentReference[oaicite:4]{index=4}

6. Beyond Simple Dominance 🌈

6.1 Incomplete Dominance 🌸

Snapdragon cross: red (RR) × white (rr) → F1 pink (Rr). Self-pollination gives 1 red : 2 pink : 1 white. The heterozygote shows an intermediate color. :contentReference[oaicite:5]{index=5}

6.2 Co-dominance 🩸

Human ABO blood group gene I has three alleles: IA, IB, i.

GenotypeBlood Type
IAIA, IAiA
IBIB, IBiB
IAIBAB (both sugars expressed)
iiO (no sugar)

With IAIB, both A and B sugars appear together—no blending, true co-dominance. :contentReference[oaicite:6]{index=6}

6.3 Multiple Alleles & Pleiotropy 🌀

  • ABO system shows multiple alleles—three versions of one gene exist in the population.
  • One gene can affect more than one trait. Example: pea seed gene B/b controls both starch-grain size and seed shape. :contentReference[oaicite:7]{index=7}

Important Concepts for NEET 🚀

  • The monohybrid 3 : 1 phenotype and 1 : 2 : 1 genotype ratios.
  • Law of Segregation explains why recessive traits re-appear in F2.
  • A test cross (dominant × recessive) instantly reveals unknown genotypes.
  • Recognize complete dominance vs. incomplete dominance vs. co-dominance.
  • Multiple alleles (ABO) and pleiotropy (starch gene) widen inheritance patterns.

Happy studying and keep exploring genetics 😊!